Ubiquinone biosynthesis protein COQ7 homolog; also known as Coenzyme Q biosynthesis protein 7 homolog; Timing protein clk-1 homolog and COQ7; is a mitochondrion inner membrane and peripheral membrane protein which belongs to theCOQ7 family. It is expressed dominantly in heart and skeletal muscle. COQ7 is synthesized as a preprotein that is imported into the mitochondrial matrix; where the sequence is cleaved off and the mature protein becomes loosely associated with the inner membrane. This enzyme is responsible for the hydroxylation of 5-demethoxyubiquinone to 5-hydroxyubiquinone. Human COQ7 protein is mostly helical; and contains an alpha-helical membrane insertion. It has a potential N-glycosylation site; a phosphorylation site for protein kinase C and another for casein kinase II; and three N-myristoylation sites. COQ7 is involved in lifespan determination in ubiquinone-independent manner. It is also involved in ubiquinone biosynthesis. COQ7 is potential central metabolic regulator.

Codice: PKSH030873_100μg | Marca: Elabscience | Confezionamento: 100μg