The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bicarbonate and protons, a reversible reaction that takes part in maintaining acid-base balance in blood and other tissues. The carbonic anhydrasekl (CA) family consists of at least 11 enzymatically active members and a few inactive homologous proteins. Carbonic anhydrase protein (CA) VIII, which is a member of the CA gene family, has been shown to have no catalytic CA activity and its biological function is still unknown. Increased expression of CA-RP VIII was observed in 78% of colorectal carcinomas. It suggested that CA-RP VIII plays a role in the process of invasion in colorectal cancer.

Codice: PKSH031586_1mg | Marca: Elabscience | Confezionamento: 1mg

Specie: Human

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Codice: PKSH031586_1mg
Marca: Elabscience
Specie target: Human
Host: E.coli
Confezionamento: Lyophilized from sterile PBS, 15% glycerol, pH 7.5<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
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Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Applicazione: Enzyme
Ig target: CA-VIII;CA8;CALS;CAMRQ3;CARP;Carbonic Anhydrase VIII;Carbonic Anhydrase-Related Protein;MGC120502;MGC99509
Area di ricerca: Cancer

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