Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone; articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions; including the control of cell growth; cell proliferation; cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family members. It has been found that TGFβ-1 is frequently upregulated in tumor cells. Mutations in this gene results in Camurati-Engelmann disease.

Dettagli prodotto

• Codice: PKSH032007_50μg
• Marca: Elabscience
• Specie target: Human
• Host: CHO Stable Cells
• Confezionamento: Lyophilized from a 0.2 μm filtered solution of 50mM Glycine-HCl, 150mM NaCl, pH 2.5.<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Applicazione: Cell culture
• Simbolo target: TGFB1;TGF-beta 1
• Ig target: CED;DPD1;LAP;Latency-Associated Peptide;TGF-Beta-1;TGF-beta 1;TGFB;TGFB1;Transforming Growth Factor Beta-1
• Area di ricerca: Signal Transduction;Cell biology;Cardiovascular;Cancer;metabolism;Stem cells