BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is a important component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex. In mammalian cells BAG1, BAG2, and BAG3 bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.

Codice: PKSH032114_50μg | Marca: Elabscience | Confezionamento: 50μg

Specie: Human

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Codice: PKSH032114_50μg
Marca: Elabscience
Specie target: Human
Host: E.coli
Confezionamento: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM EDTA, 1mM DTT, 10% Glycerol, pH8.0.
Link: Apri link
Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Simbolo target: BAG2
Ig target: BAG Family Molecular Chaperone Regulator 2;BAG-2;BAG2;Bcl-2-Associated Athanogene 2
Area di ricerca: Signal Transduction;Cell biology;Cancer;metabolism;

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