Carbonic Anhydrase 7 (CA7) is a member of the alpha-carbonic anhydrase family. Alpha-carbonic anhydrase is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Furthermore; Alpha-carbonic anhydrase is associated with many biological processes; including calcification; respiration; bone resorption; acid-base balance and the formation of aqueous humor. CA7 is activated by histamine; L-adrenaline; L- and D-histidine; and L- and D-phenylalanine; but it is inhibited coumarins; sulfonamide derivatives such as acetazolamide (AZA) by saccharin and Foscarnet.