Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin related glycoproteins. They play critical roles in cell–cell recognition. CEACAM5; also called CEA and CD66e; is characterized by having seven extracellular Ig domains and a glycosylphosphatidylinositol (GPI) anchor. CEACAM5 is expressed primarily by epithelial cells; and functions as a calcium-independent adhesion molecule through homophilic and heterophilic interactions with CEACAM1. Studies have shown that CEACAM5 is overexpressed in a majority of carcinomas; and its overexpression can protect tumor cells from apoptosis. It is commonly used as a cancer marker.

Dettagli prodotto

• Codice: PKSH032237_50μg
• Marca: Elabscience
• Specie target: Human
• Host: HEK293 Cells
• Confezionamento: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Simbolo target: CEACAM5;CEA
• Ig target: CD66e;CEA;CEACAM5;Carcinoembryonic antigen;Carcinoembryonic antigen-related cell adhesion molecule 5;Meconium antigen 100
• Area di ricerca: Tags & Cell Markers;Microbiology;Cancer;immunology;Stem cells