Dipeptidase 1 (DPEP1) is a kidney membrane enzyme that belongs to the peptidase M19 family. DPEP1 is a homodimer and is inhibited by L-penicillamine. DPEP1 hydrolyzes a variety of dipeptides and is implicated in renal metabolism of glutathione and its conjugates. DPEP1 is responsible for hydrolysis of the beta-lactam ring of antibiotics; such as penem and carbapenem. DPEP1 may play an important role in the regulation of leukotriene activity. DPEP1 expression in cancer is significantly higher than that in normal tissue. However; DPEP1 expression decreased with pathological differentiation; lymph-node and distant metastasis.

Codice: PKSH032356_10μg | Marca: Elabscience | Confezionamento: 10μg

Specie: Human

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Codice: PKSH032356_10μg
Marca: Elabscience
Specie target: Human
Host: HEK293 Cells
Confezionamento: Supplied as a 0.2 μm filtered solution of PBS, 10% Glycerol, pH 7.4.
Link: Apri link
Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Simbolo target: Dipeptidase 1;DPEP1
Ig target: DPEP1;Dehydropeptidase-I;Dipeptidase 1;MBD1;MDP;Microsomal Dipeptidase;RDP;Renal Dipeptidase;hRDP
Area di ricerca: Cell biology;Cancer

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