DNA Fragmentation Factor Subunit Alpha (DFFA). DFFA exists as a heterodimer (DFF) with DFFB. DFF is activated once DFFA is cleaved by Caspase-3. The cleaved fragments of DFFA detach from DFFB (the active component of DFF), which in turn triggers DNA fragmentation as well as chromatin condensation during apoptosis. A reduced level of DFFA detected in ovarian endometriosis may be a part of an apoptosis-resistant mechanism enhancing the disease progression.

Codice: PKSH032359_10μg | Marca: Elabscience | Confezionamento: 10μg

Specie: Human

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Codice: PKSH032359_10μg
Marca: Elabscience
Specie target: Human
Host: E.coli
Confezionamento: Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Link: Apri link
Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Simbolo target: DFFA
Ig target: DFF-45;DFF1;DFF45;DFFA;DNA Fragmentation Factor 45 kDa Subunit;DNA Fragmentation Factor Subunit Alpha;H13;ICAD;Inhibitor of CAD
Area di ricerca: Cell biology;Cancer;epigenetics and nuclear signal;metabolism

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