Elafin is a secreted protein. Elafin consists of two domains: the transglutaminase substrate domain (cementoin moiety) and the elastase inhibitor domain. The transglutaminase substrate domain serves as an anchor to localize Elafin covalently to specific sites on extracellular matrix proteins. It is shown that Elafin can be used as a biomarker for graft versus host disease of the skin. Elafin is expressed in the skin during wound healing through activation of the epidermal growth factor receptor. Elafin may prevent elastase-mediated tissue proteolysis.

Codice: PKSH032375_10μg | Marca: Elabscience | Confezionamento: 10μg

Specie: Human

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Codice: PKSH032375_10μg
Marca: Elabscience
Specie target: Human
Host: HEK293 Cells
Confezionamento: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 7.5.
Link: Apri link
Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Simbolo target: PI3;Elafin
Ig target: ESI;Elafin;Elastase-Specific Inhibitor;PI-3;PI3;Peptidase Inhibitor 3;Protease inhibitor WAP3;SKALP;Skin-Derived Antileukoproteinase;WAP Four-Disulfide Core Domain Protein 14;WAP3;WFDC14
Area di ricerca: Microbiology;Cell biology;Cancer;immunology

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