ERO1-Like Protein α (ERO1L) is an enzyme that belongs to the EROs family. ERO1L is expressed at high level in esophagus and upper digestive tract. ERO1L is an essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. ERO1L acts by oxidizing directly P4HB/PDI isomerase through a direct disulfide exchange. It associates with ERP44, demonstrating that it does not oxidize all PDI related proteins and can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. ERO1L may be responsible for a significant proportion of reactive oxygen species (ROS) in the cell. ERO1L responses to temperature stimulus, protein thiol-disulfide exchange, protein folding with or without chaperone cofactor and transport.

Codice: PKSH032401_50μg | Marca: Elabscience | Confezionamento: 50μg

Specie: Human

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Codice: PKSH032401_50μg
Marca: Elabscience
Specie target: Human
Host: HEK293 Cells
Confezionamento: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
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Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Simbolo target: ERO1A;ERO1L
Ig target: ERO1-L;ERO1-L-Alpha;ERO1-Like Protein Alpha;ERO1L;Endoplasmic Oxidoreductin-1-Like Protein;Oxidoreductin-1-L-Alpha
Area di ricerca: Signal Transduction;

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