6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 is an enzyme that in humans is encoded by the PFKFB1 gene. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. It belongs to the phosphoglycerate mutase family. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.

Codice: PKSH032459_10μg | Marca: Elabscience | Confezionamento: 10μg

Specie: Human

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Codice: PKSH032459_10μg
Marca: Elabscience
Specie target: Human
Host: HEK293 Cells
Confezionamento: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5% Trehalose, 1mM EDTA, pH 7.8.
Link: Apri link
Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Simbolo target: PFKFB1
Ig target: 6-P2ase liver isozyme;6-bisphosphatase;6-bisphosphatase 1;6-phosphofructo-2-kinase/fructose-2;6PF-2-K/Fru-2;F6PK;Fructose-2;PFKFB1;PFRX
Area di ricerca: Signal Transduction;Cardiovascular;Neuroscience;Cancer;metabolism;

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