Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-bound IL-15 receptor β and γ heterodimers and enables signaling to cells.

Dettagli prodotto

• Codice: PKSH032566_50μg
• Marca: Elabscience
• Specie target: Human
• Host: HEK293 Cells
• Confezionamento: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Applicazione: Cell culture
• Simbolo target: IL15RA;IL-15RA
• Ig target: MGC;IL15RA;CD215;alpha;CD215 antigen;IL-15 receptor subunit alpha;IL-15RA;IL-15R-alpha;interleukin 15 receptor;interleukin-15 receptor subunit alpha;MGC104179;AA690181;I15RA;IL 15R alpha;Interleukin 15 receptor alpha;Interleukin 15 receptor subunit alpha;sIL-15 receptor subunit alpha;sIL-15RA;sIL-15R-alpha;Soluble interleukin 15 receptor subunit alpha;Soluble interleukin-15 receptor subunit alpha
• Area di ricerca: Signal Transduction;Cell biology;Cancer;metabolism;