IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.

Dettagli prodotto

• Codice: PKSH032568_50μg
• Marca: Elabscience
• Specie target: Human
• Host: HEK293 Cells
• Confezionamento: Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
• Link: Apri link
• Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
• Simbolo target: IL18RAP;IL1R7
• Ig target: IL1R;ACPL;CD218b;CDw218b;IL-18RAcP;IL18RB;IL-18Rbeta;IL-18R-beta;IL-1R7;IL-1R-7;IL-1RAcPL;IL1R7;IL18RAP; IL-1RcPL; CDw218b;IL18R&beta;Accessory protein like;Accessory protein-like;CD218 antigen-like family member B;I18RA;IL 18RAcP;IL 1R accessory protein like;IL 1R7;IL 1RAcPL;IL-18 receptor accessory protein;IL18Rbeta;IL-1R accessory protein-like;Interleukin 18 receptor accessory protein;Interleukin-1 receptor 7;Interleukin-18 receptor accessory protein;Interleukin-18 receptor accessory protein-like;Interleukin-18 receptor beta;Interleukin-18 receptor beta chain
• Area di ricerca: Cancer;immunology