Inositol Monophosphatase 1 (IMPA1) belongs to the inositol monophosphatase family. IMPA1 is responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides, IMPA1 can use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2-AMP as substrates. IMPA1 has been implicated as the pharmacological target for lithium action in brain. IMPA1 shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. In addition, IMPA1 plays a improtant role in intracellular signal transduction.

Codice: PKSH032590_50μg | Marca: Elabscience | Confezionamento: 50μg

Specie: Human

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Codice: PKSH032590_50μg
Marca: Elabscience
Specie target: Human
Host: E.coli
Confezionamento: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.25.
Link: Apri link
Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Simbolo target: IMP1;IMPA1
Ig target: IMP 1;IMPA;IMPA1;IMPase 1;Inositol Monophosphatase 1;Inositol-1(or 4)-Monophosphatase 1;Lithium-Sensitive Myo-Inositol Monophosphatase A1
Area di ricerca: Signal Transduction;Neuroscience;metabolism;

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