Interleukin-28B; also known as Cytokine Zcyto22; Interferon lambda-3; Interferon lambda-4; IFNL3; IFNL4; ZCYTO22 and IL28B; is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition; IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.

Dettagli prodotto

• Codice: PKSH032637_10μg
• Marca: Elabscience
• Specie target: Human
• Host: HEK293 Cells
• Confezionamento: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, pH 7.4.<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
• Link: https://www.elabscience.com/p-recombinant_human_ifn_λ3/il_28b_protein_(human_cells,_his_tag)-pksh032637
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Simbolo target: IFN-λ3;IL-28B
• Ig target: Cytokine Zcyto;ZCYTO;IFNL3;IFN-lambda-3;IFN-lambda-4;IL-28B;IL-28C;IL28B;IL28C;Cytokine Zcyto22;IFNL4;IFN-lambda 3;interferon lambda 3;Interferon Lambda-3;Interferon Lambda-4;Interleukin-28B;Interleukin-28C;ZCYTO22
• Area di ricerca: Signal Transduction;Microbiology;immunology;