Isocitrate Dehydrogenase [NADP] Cytoplasmic (IDH1) belongs to the isocitrate and isopropylmalate dehydrogenases family. IDH1 exists as a homodimer; binding one magnesium or manganese ion per subunit. Mutations of IDH1 have been shown to cause metaphyseal chondromatosis with aciduria and are involved in the development of glioma IDH plays a role in the regeneration of NADPH for intraperoxisomal reductions; such as the conversion of 2; 4-dienoyl-CoAs to 3-enoyl-CoAs; as well as in peroxisomal reactions that consume 2-oxoglutarate; namely the α-hydroxylation of phytanic acid.

Codice: PKSH032659_50μg | Marca: Elabscience | Confezionamento: 50μg

Specie: Human

Torna alla lista Apri link

Codice: PKSH032659_50μg
Marca: Elabscience
Specie target: Human
Host: E.coli
Confezionamento: Supplied as a 0.2 μm filtered solution of 50mM Tris, 200mM NaCl, 10% glycerol, pH8.0.
Link: Apri link
Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Simbolo target: IDH1
Ig target: Cytosolic NADP-Isocitrate Dehydrogenase;IDH;IDH1;IDP;Isocitrate Dehydrogenase [NADP] Cytoplasmic;NADP(+)-Specific ICDH;Oxalosuccinate Decarboxylase;PICD
Area di ricerca: Signal Transduction;Cancer;metabolism;

Scheda prodotto