Tumor necrosis factor receptor superfamily member 3; also known as Lymphotoxin-beta receptor;Tumor necrosis factor C receptor;Tumor necrosis factor receptor 2-related protein;Tumor necrosis factor receptor type III;LTBR;TNFCR; TNFR3 and TNFRSF3; is a member of the tumor necrosis factor (TNF) family of receptors. LTBR is a single-pass type I membrane protein and contains four TNFR-Cys repeats. It is expressed on the surface of most cell types; but not on T and B lymphocytes. LTBR and its ligand play a role in the development and organization of lymphoid tissue and transformed cells. Activation of LTBR can trigger apoptosis. In addition; LTBR can lead to the release of the cytokine interleukin 8.
Confezionamento: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Simbolo target: LTBR;TNFRSF3
Ig target: D12S370;LTBR;Lymphotoxin-Beta Receptor;TNF-RIII;TNFCR;TNFR-III;TNFR3;TNFRSF3;Tumor Necrosis Factor C Receptor;Tumor Necrosis Factor Receptor 2-Related Protein;Tumor Necrosis Factor Receptor Superfamily Member 3;Tumor Necrosis Factor Receptor Type III
Area di ricerca:Signal Transduction;Cell biology;epigenetics and nuclear signal;
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