Protein NDRG1 is a member of the N-Myc Downregulated Gene family, which is part of the α/β Hydrolase superfamily. Protein NDRG1 is a cytoplasmic protein that is involved in stress responses, hormone responses, cell growth and differentiation. Protein NDRG1 is necessary for p53-mediated caspase activation and apoptosis. Protein NDRG1 mutuations are reported to be the cause for hereditary motor and sensory neuropathy-Lom. Decreased NDRG1 expression in glioma is linked to tumor progression; overexpression of NDRG1 is connected to malignant status of esophageal cancer.
Confezionamento: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Simbolo target: NDRG1
Ig target: CAP43;DRG-1;DRG1;Differentiation-Related Gene 1 Protein;N-myc Downstream-Regulated Gene 1 Protein;NDRG1;Nickel-Specific Induction Protein Cap43;Protein NDRG1;RTP;Reducing Agents and Tunicamycin-Responsive Protein;Rit42
Area di ricerca:Signal Transduction;Neuroscience;Cancer;epigenetics and nuclear signal;
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