FKBP4 act as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. FKBP4 may play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments, it also may have a protective role against oxidative stress in mitochondria. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening.

Dettagli prodotto

• Codice: PKSH032877_10μg
• Marca: Elabscience
• Specie target: Human
• Host: E.coli
• Confezionamento: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 10% Glycerol, pH 8.0.
• Link: Apri link
• Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
• Simbolo target: FKBP4
• Ig target: 51kDa FK506-binding protein;59kDa immunophilin;FK506-binding protein 4;FKBP4;FKBP59;HSP-binding immunophilin;Peptidyl-prolyl cis-trans isomerase FKBP4;Rotamase;immunophilin FKBP52
• Area di ricerca: Signal Transduction;epigenetics and nuclear signal;