KLK3; also known as APS; is short for Prostate-specific antigen. It is a 261 aa. protein which belongs to the peptidase S1 family and Kallikrein subfamily. This protein has 5 isforms produced by alternative splicing. It is a secreted protein and can forms a heterodimer with SERPINA5 which can inhibit its activity. KLK3 is also strongly inhibited by Zn2+; 100 times more abundant in semen than in serum. This inhibition is relieved by exposure to semenogelins; which are avid zinc binders. KLK3 can hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.

Codice: PKSH032949_10μg | Marca: Elabscience | Confezionamento: 10μg

Specie: Human

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Codice: PKSH032949_10μg
Marca: Elabscience
Specie target: Human
Host: HEK293 Cells
Confezionamento: Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, 10mM CaCl<sub>2</sub>, 150mM NaCl, 0.05% Brij 35, pH 7.5.
Link: Apri link
Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Simbolo target: PSA;KLK3
Ig target: APS;Gamma-Seminoprotein;Hk3;KLK2A1;Kallikrein-3;P-30 Antigen;PSA;Prostate-Specific Antigen;Semenogelase;Seminin
Area di ricerca: Signal Transduction;Tags & Cell Markers;Neuroscience;Cancer;immunology;

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