Protein-Arginine Deiminase Type-4 (PADI4) belongs to the Protein Arginine Deiminase family. PADI4 is expressed in eosinophils and neutrophils, but it is not expressed in peripheral monocytes or lymphocytes. PADI4 catalyzes the citrullination/deimination of arginine residues of proteins. In addition, PADI4 may play an important role in tumourigenesis. Genetic variations in PADI4 are a cause of susceptibility to rheumatoid arthritis (RA), which is a systemic inflammatory disease with autoimmune features and a complex genetic component.

Codice: PKSH032973_50μg | Marca: Elabscience | Confezionamento: 50μg

Specie: Human

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Codice: PKSH032973_50μg
Marca: Elabscience
Specie target: Human
Host: E.coli
Confezionamento: Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, 500mM NaCl, pH 7.5.
Link: Apri link
Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Simbolo target: PADI4
Ig target: HL-60 PAD;PADI4;PADI5;PDI5;Peptidylarginine Deiminase IV;Protein-Arginine Deiminase Type-4;Protein-arginine Deiminase type IV
Area di ricerca: Signal Transduction;epigenetics and nuclear signal;metabolism;

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