Superoxide Dismutase (SOD2) is a number of the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. The SOD2 protein transforms toxic superoxide and a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. Genetic variation in SOD2 is associated with microvascular complications of diabetes type 6 (MVCD6); idiopathic cardiomyopathy (IDC); sporadic motor neuron disease; and cancer. SOD2 destroys superoxide anion radicals which are usually produced within the cells and which are toxic to biological systems.

Codice: PKSH033072_10μg | Marca: Elabscience | Confezionamento: 10μg

Specie: Human
Dettagli prodotto
  • Codice: PKSH033072_10μg
  • Marca: Elabscience
  • Specie target: Human
  • Host: E.coli
  • Confezionamento: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, 50% Glycerol, pH 8.0.
  • Link: Apri link
  • Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Simbolo target: SOD2;Mn-SOD
  • Ig target: SOD2;Superoxide Dismutase [Mn] Mitochondrial
  • Area di ricerca: Signal Transduction;Cell biology;Cardiovascular;Neuroscience;Cancer;metabolism;