Valosin-Containing Protein (VCP) is a nuclear protein that belongs to the AAA ATPase family. VCP is a putative ATP-binding protein involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxisomes. It is necessary for the fragmentation of Golgi stacks during mitosis and their reassembly after mitosis. VCP has been implicated in a number of cellular events that are regulated during mitosis, including homotypic membrane fusion, spindle pole body function, and ubiquitin-dependent protein degradation. VCP participates in the formation of the transitional endoplasmic reticulum (tER) and regulates E3 ubiquitin-protein ligase activity of RNF19A.

Codice: PKSH033203_50μg | Marca: Elabscience | Confezionamento: 50μg

Specie: Human

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Codice: PKSH033203_50μg
Marca: Elabscience
Specie target: Human
Host: E.coli
Confezionamento: Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, pH8.0.
Link: Apri link
Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Simbolo target: VCP
Ig target: 15S Mg(2+)-ATPase p97 Subunit;TER ATPase;Transitional Endoplasmic Reticulum ATPase;VCP;Valosin-Containing Protein
Area di ricerca: Signal Transduction;Neuroscience;metabolism;

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