β-Defensin 4A is a membrane-active cationic peptide that functions in inflammation and innate immune responses. There are at least 30 β-Defensins, which are distinguished from α-Defensins by the connectivity pattern of their three intermolecular disulfide bonds. Members of the Defensin family are highly similar in protein sequence. This gene encodes Defensin, DEFB4;, which has broad-spectrum antimicrobial activity and may play an important role in innate epithelial defense. They are highly expressed in skin and tonsils, and to a lesser extent in trachea, uterus, kidney, thymus, adenoid, pharynx and tongue. β-Defensin 4A has low expression in salivary gland, bone marrow, colon, stomach, polyp and larynx. No expression in small intestine. The 45 amino acid mature human BD3 shares 38% and 33% amino acid sequence identity with mouse and rat BD3, respectively.

Codice: PKSH033266_10μg | Marca: Elabscience | Confezionamento: 10μg

Specie: Human

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Codice: PKSH033266_10μg
Marca: Elabscience
Specie target: Human
Host: E.coli
Confezionamento: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
Link: https://www.elabscience.com/p-recombinant_human_β_defensin_4a/defb4a_protein-pksh033266
Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Simbolo target: β-Defensin 4A;DEFB4A
Ig target: BD-2;Beta 2;Beta-Defensin 2;Beta-Defensin 4A;DEFB102;DEFB2;DEFB4;DEFB4A;DEFB4B;Defensin;SAP1;Skin-Antimicrobial Peptide 1;hBD-2
Area di ricerca: Microbiology

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