Peptidyl-Prolyl Cis-Trans Isomerase-Like 1 (PPIase) belongs to the cyclophilin-type PPIase family. PPIases can accelerate the folding of proteins and catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. PPIase is a ubiquitous protein and has highly expression in heart ;skeletal and muscle. PPIase contains a PPIase cyclophilin-type domain and four Cyclosporin A binding regions. PPIase might play an important role in proliferation of cancer cells through modulation of phosphorylation of stathmin. It is suggested that PPIase can act as as a novel molecular target for colon-cancer therapy.

Dettagli prodotto

• Codice: PKSH033304_10μg
• Marca: Elabscience
• Specie target: Human
• Host: E.coli
• Confezionamento: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.0.
• Link: Apri link
• Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
• Simbolo target: PPIase;PPIL1
• Ig target: CGI;UNQ;PRO;PPIL;CYPL;PPIase FKBP;Rotamase PPIL;FK506-Binding Protein;Peptidyl-Prolyl Cis-Trans Isomerase FKBP;Peptidyl-Prolyl Cis-Trans Isomerase-Like;PPIL1;CGI-124;CYPL1;PPIase;hCyPX;23 kDa FK506-Binding Protein;23 kDa FKBP;FK506-Binding Protein 7;FKBP23;FKBP-23;FKBP7;FKBP-7;Peptidyl-Prolyl Cis-Trans Isomerase FKBP7;Peptidyl-Prolyl Cis-Trans Isomerase-Like 1;PPIase FKBP7;Rotamase;Rotamase PPIL1;UNQ2425;PRO4984;peptidylprolyl isomerase like 1
• Area di ricerca: Signal Transduction;epigenetics and nuclear signal;immunology;