Interleukin 1 receptor-like 1(IL1RL1) is a member of the interleukin-1 receptor family, Contains 3 Ig-like C2-type domains and 1 TIR domain. It is highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. IL1RL1 is a receptor for interleukin-33, its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. IL1RL1 may possibly be involved in helper T-cell function. Soluble IL1RL1 also acts as a negative regulator of Th2 cytokine production, it directly implicated in the progression of cardiac disease.

Dettagli prodotto

• Codice: PKSH033314_10μg
• Marca: Elabscience
• Specie target: Human
• Host: HEK293 Cells
• Confezionamento: Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Simbolo target: IL1RL1;ST2
• Ig target: FIT;DER;IL1RL;IL-1 R;IL1RL1;DER4;FIT-1;IL33R;ST2;ST2L;ST2V;T1;IL-1 R4;DER-4;FIT 1;Growth stimulation expressed;Growth stimulation expressed gene 2;homolog of mouse growth stimulation-expressed;IL-1R4;ILRL1;Interleukin 1 receptor like 1;interleukin 1 receptor related protein;Interleukin-1 receptor-like 1;Protein ST2;T1 protein
• Area di ricerca: Cardiovascular Immunology