Ubiquitin-Conjugating Enzyme E2 H (UBE2H) belongs to the E2 Ubiquitin-Conjugating Enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes; or E1s; ubiquitin-conjugating enzymes; or E2s; and ubiquitin-protein ligases; or E3s. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro. UBE2H is the human homolog to the yeast DNA repair gene RAD6; which is induced by DNA damaging reagents. UBE2H has been associated with cancer-induced cachexia and with the regulation of sepsis-induced muscle proteolysis.

Codice: PKSH033316_50μg | Marca: Elabscience | Confezionamento: 50μg

Specie: Human

Torna alla lista Apri link

Codice: PKSH033316_50μg
Marca: Elabscience
Specie target: Human
Host: E.coli
Confezionamento: Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5.
Link: Apri link
Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Simbolo target: Ube2H
Ig target: E2-20K;GID3;UBC8;UBCH;UBCH2;UBE2H;UbcH2;Ubiquitin Carrier Protein H;Ubiquitin-Conjugating Enzyme E2 H;Ubiquitin-Conjugating Enzyme E2-20K;Ubiquitin-Protein Ligase H
Area di ricerca: Cell biology;epigenetics and nuclear signal

Scheda prodotto