Ubiquitin-Conjugating Enzyme E2 T (UBE2T) is a ligase that belongs to the Ubiquitin-Conjugating Enzyme family. UBE2T accepts the ATP-dependent ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro; UBE2T is able to catalyze polyubiquitination using all 7 ubiquitin Lys residues; but may prefer 'Lys-11'-; 'Lys-27'-; 'Lys-48'- and 'Lys-63'-linked polyubiquitination. UBE2T is an important factor of the Faconi anemia pathway of DNA damage repair and; upon self-inactivation; may negatively regulate the Faconi pathway.

Codice: PKSH033331_10μg | Marca: Elabscience | Confezionamento: 10μg

Specie: Human
Dettagli prodotto
  • Codice: PKSH033331_10μg
  • Marca: Elabscience
  • Specie target: Human
  • Host: E.coli
  • Confezionamento: Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 2mM DTT, 10% Glycerol, pH 7.5.
  • Link: Apri link
  • Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Simbolo target: UBE2T
  • Ig target: Cell Proliferation-Inducing Gene 50 Protein;UBE2T;Ubiquitin Carrier Protein T;Ubiquitin-Conjugating Enzyme E2 T;Ubiquitin-Protein Ligase T
  • Area di ricerca: Cell biology;epigenetics and nuclear signal