Complement Component 1Q Subcomponent-Binding Protein (C1QBP) is a nucleus protein that belongs to the MAM33 family. C1QBP is known to bind to the globular heads of C1q molecules and inhibit C1 activation. Mitochondrial C1QBP is a critical mediator of p14ARF-induced apoptosis. C1QBP functions as a chemotactic factor for immature dendritic cells, and migration is mediated through ligation of both C1QBP and cC1qR/CR. C1QBP overexpression successfully blocks mRNA accumulation from the adenovirus major late transcription unit (MLTU) and stimulates RNA polymerase II carboxy-terminal domain phosphorylation in virus-infected cells.
Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Simbolo target: C1QBP
Ig target: ASF/SF2-Associated Protein p32;C1QBP;C1qBP;Complement Component 1 Q Subcomponent-Binding Protein Mitochondrial;GC1QBP;Glycoprotein gC1qBP;HABP1;Hyaluronan-Binding Protein 1;Mitochondrial Matrix Protein p32;SF2P32;gC1q-R Protein;gC1qR;p33
Area di ricerca:Microbiology;immunology
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