V-Set and Immunoglobulin Domain-Containing Protein 2 (VSIG2) is presumably a 50-60 kDa single-pass type I transmembrane (glyco)protein which contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. VSIG2 is highly expressed in the stomach; colon; prostate; trachea and thyroid glands and weakly in bladder and lung. V-set domains are Ig-like domains resembling the antibody variable domain. V-set domains are found in diverse protein families; including immunoglobulin light and heavy chains; in several T-cell receptors such as CD2 (Cluster of Differentiation 2); CD4; CD80; and CD86; in myelin membrane adhesion molecules; in junction adhesion molecules (JAM); in tyrosine-protein kinase receptors; and in the programmed cell death protein 1 (PD1). It shows expression in stomach and prostate by Northern blot; and likely participates in cell adhesion. Human VSIG2 precursor is 327 amino acids in length.

Codice: PKSH033363_10μg | Marca: Elabscience | Confezionamento: 10μg