Asialoglycoprotein Receptor 1 (ASGPR1) is an endocytic recycling receptor; belongs to the long-form subfamily of the C-type/Ca2+-dependent lectin family. ASGPR consists of two noncovalently-linked subnits; ASGPR1 and ASGPR2. ASGPR1 mediates the endocytosis of plasma glycoproteins; recognizes terminal galactose and N-acetylgalactosamine units. When the ligand binds to to ASGPR1; results in the complex is internalized and transported to a sorting organelle; then ASGPR1 and ligand can be disassociated; ASGPR1 returns to the cell membrane surface.

Dettagli prodotto

• Codice: PKSH033403_10μg
• Marca: Elabscience
• Specie target: Human
• Host: HEK293 Cells
• Confezionamento: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Simbolo target: ASGR1;ASGPR1
• Ig target: ASGP-R 1;ASGPR 1;ASGR1;Asialoglycoprotein Receptor 1;C-Type Lectin Domain Family 4 Member H1;CLEC4H1;HL-1;Hepatic Lectin H1
• Area di ricerca: Signal Transduction;Tags & Cell Markers;