Human Kallikrein 11 (KLK11) is a member of tissue kallikrein family which are extracellular serine proteases consisting of 15 members. Two isoforms of KLK11 are differentially expressed. Isoform 1 is predominantly expressed in brain and isoform 2 is preferentially expressed in prostate. Isoform 1 consists of a signal peptide;a short pro peptide and the mature chain.Isoform 2 contains an extra 32 amino acid N terminal to full-length isoform 1.KLK11 is a novel marker for ovarian and prostate cancer carcinomas. KLK11 can be activated by thermolysin and is active against a thioester substrate.

Codice: PKSH033404_10μg | Marca: Elabscience | Confezionamento: 10μg

Specie: Human

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Codice: PKSH033404_10μg
Marca: Elabscience
Specie target: Human
Host: HEK293 Cells
Confezionamento: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 2mM CaCl<sub>2</sub>, pH 8.0.
Link: Apri link
Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Simbolo target: Kallikrein 11;KLK11
Ig target: Hippostasin;KLK11;Kallikrein-11;PRSS20;Serine Protease 20;TLSP;Trypsin-Like Protease;hK11
Area di ricerca: Signal Transduction;Cell biology;Cancer;

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