Carnosine Dipeptidase 1 (CNDP1) belongs to the M20 metalloprotease family. CNDP1 is specifically expressed in the brain; serum and adult nervous central system. It is identified as human carnosinase. CNDP1 contains trinucleotide (CTG) repeat length polymorphism in the coding region and is inhibited by the metal chelator 1;10-o-phenantrolin. In addition; CNDP1 can hydrolyse the beta-Ala|-His dipeptide (carnosine); anserine; Xaa-|-His dipeptides and other dipeptides including homocarnosine. CNDP1 deficiency has been associated with homocarnosinosis disease.

Codice: PKSH033451_10μg | Marca: Elabscience | Confezionamento: 10μg

Specie: Human

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Codice: PKSH033451_10μg
Marca: Elabscience
Specie target: Human
Host: HEK293 Cells
Confezionamento: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 7.5.
Link: Apri link
Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Simbolo target: CNDP1
Ig target: Beta-Ala-His Dipeptidase;CN1;CNDP Dipeptidase 1;CNDP1;CPGL2;Carnosine Dipeptidase 1;Glutamate Carboxypeptidase-Like Protein 2;HsT2308;Serum Carnosinase
Area di ricerca: Signal Transduction;Cancer;

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