MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 crucial in connective tissue remodeling.[3] The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation.

Codice: PKSH033591_50μg | Marca: Elabscience | Confezionamento: 50μg

Specie: Human
Dettagli prodotto
  • Codice: PKSH033591_50μg
  • Marca: Elabscience
  • Specie target: Human
  • Host: HEK293 Cells
  • Confezionamento: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 0.05% Brij35, 10% Glycerol, pH 7.5.
  • Link: Apri link
  • Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Simbolo target: MMP-3
  • Ig target: CHDS6;MMP-3;MMP3;Matrix metalloproteinase-3;SL-1;STMY;STMY1;STR1;Stromelysin-1;Transin-1
  • Area di ricerca: Signal Transduction;Cell biology;Cardiovascular;Cancer;