Interleukin-1 receptor accessory protein-like 1; also known as IL1RAPL1; can be detected at low levels in heart; skeletal muscle; ovary; skin; amygdala; caudate nucleus; corpus callosum; hippocampus; substantia nigra and thalamus. IL1RAPL1 functions as a homodimer; it interacts with NCS1; PTPRD. This interaction is PTPRD-splicing-dependent and induces pre- and post-synaptic differentiation of neurons and is required for IL1RAPL1-mediated synapse formation. During dendritic spine formation; it can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD.

Dettagli prodotto

• Codice: PKSH033634_10μg
• Marca: Elabscience
• Specie target: Human
• Host: HEK293 Cells
• Confezionamento: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Simbolo target: IL-1R8;IL1RAPL1
• Ig target: IL1R;OPHN;TIGIRR;MRX;IL1RAPL1;IL1R8;IL1RAPL;MRX10;MRX21;MRX34;OPHN4;TIGIRR-2;IL1RAPL-1;IL-1RAPL-1;IL-1-RAPL-1;Interleukin-1 Receptor Accessory Protein-Like 1;Oligophrenin-4;Three Immunoglobulin Domain-Containing IL-1 Receptor-Related 2;X-Linked Interleukin-1 Receptor Accessory Protein-Like 1
• Area di ricerca: Neuroscience