Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells; B cells; macrophages; mast cells; endothelial cells and fibroblasts) in response to cytokine of immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors; GM-CSF is also a growth factor for erythroid; megakaryocyte and eosinophil progenitors. On mature hematopoietic; monocytes/ macrophages and eosinophils. GM-CSF has a functional role on non-hematopoitic cells. It can induce human endothelial cells to migrate and proliferate. Additionally; GM-CSF can also stimulate the proliferation of a number of tumor cell lines; including osteogenic sarcoma; carcinoma and adenocarcinoma cell lines.

Codice: PKSH033662_20μg | Marca: Elabscience | Confezionamento: 20μg

Specie: Human

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Codice: PKSH033662_20μg
Marca: Elabscience
Specie target: Human
Host: E.coli
Confezionamento: Lyophilized from sterile PBS,pH 8.0.<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
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Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Applicazione: Cell culture
Simbolo target: GM-CSF;CSF2
Ig target: CSF;CSF2;Colony-Stimulating Factor;GM-CSF;GMCSF;Granulocyte-Macrophage Colony-Stimulating Factor;Molgramostin;Sargramostim
Area di ricerca: immunology

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