Brain-Derived Neurotrophic Factor (BDNF) is a member of the neurotrophin family. Along with other structurally related neurotrophic factors NGF; NT-3 and NT-4; BDNF binds with high affinity to the TrkB kinase receptor. It also binds with the LNGFR (for low-affinity nerve growth factor receptor; also known as p75). BDNF promotes the survival; growth and differentiation of neurons. It serves as a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease.

Dettagli prodotto

• Codice: PKSH033808_100μg
• Marca: Elabscience
• Specie target: Human/Mouse/Rat
• Host: E.coli
• Confezionamento: Lyophilized from sterile 20 mM sodium citrate, 0.2 M NaCl, pH 3.5. <br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Applicazione: Cell culture
• Simbolo target: BDNF
• Ig target: Abrineurin;BDNF;Brain-Derived Neurotrophic Factor
• Area di ricerca: Cardiovascular;Neuroscience;metabolism