B cell maturation protein (BCMA) is a type III membrane protein which belongs to the TNF receptor superfamily (TNFRSF17). BCMA contains one extracellular cysteine rich domain, as well as TACI. Human BCMA is a 184 amino acid (aa) protein consisting of a 54 aa extracellular domain, a 23 aa transmembrane domain, and a 107 aa intracellular domain. Mouse and human BCMA share 62% amino acid identity. BCMA is mainly expressed in immune organs and mature B cell lines. BCMA appears to be localized to the Golgi compartment. BCMA may play an important role in B cell development, function and regulation.

Dettagli prodotto

• Codice: PKSH033857_100μg
• Marca: Elabscience
• Specie target: Human
• Host: HEK293 Cells
• Confezionamento: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Coniugazione: Biotinylated
• Simbolo target: BCMA;TNFRSF17
• Ig target: B-cell maturation protein;CD269;TNFRSF17;Tumor necrosis factor receptor superfamily member 17
• Area di ricerca: Signal Transduction;Cancer;immunology;