CD38, also known as ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, is a Signal-anchor for type II membrane protein. CD38 is able to transform NAD+ to ADP-D-ribose and nicotinamide. It also can transform NADP+ to nicotinate-adenine dinucleotide phosphate and nicotinamide. CD38 is expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.

Codice: PKSH033880_100μg | Marca: Elabscience | Confezionamento: 100μg

Specie: HumanConiugazione: Biotinylated

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Codice: PKSH033880_100μg
Marca: Elabscience
Specie target: Human
Host: HEK293 Cells
Confezionamento: Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Link: Apri link
Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Coniugazione: Biotinylated
Simbolo target: CD38
Ig target: 2'-phospho-ADP-ribosyl cyclase;2'-phospho-cyclic-ADP-ribose transferase;ADP-ribosyl cyclase 1;ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1;Cyclic ADP-ribose hydrolase 1;cADPr hydrolase 1
Area di ricerca: Cancer;immunology;metabolism;Stem cells

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