Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis.PCSK9 also plays a role in neural development.

Codice: PKSM041128_50μg | Marca: Elabscience | Confezionamento: 50μg

Specie: Mouse
Dettagli prodotto
  • Codice: PKSM041128_50μg
  • Marca: Elabscience
  • Specie target: Mouse
  • Host: HEK293 Cells
  • Confezionamento: Supplied as a 0.2 μm filtered solution of 50mM HEPES, 150mM NaCl, 20% Glycerol, pH 7.4.
  • Link: Apri link
  • Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Simbolo target: PCSK9;NARC1
  • Ig target: FH3;HCHOLA3;NARC-1;Narc1;Neural Apoptosis-Regulated Convertase 1;PC9;Pcsk9;Proprotein Convertase 9;Proprotein Convertase Subtilisin/Kexin Type 9;Subtilisin/Kexin-Like Protease PC9