LYN contains one protein kinase domain, one SH2 domain, one SH3 domain, and the protein kinase domain plays an important role in its localization in the cell membrane. LYN is also thought to participate in signal transduction from cell surface receptors that lack intrinsic tyrosine kinase activity. In addition, LYN is associated with a number of cell surface receptors including the B cell antigen receptor and immunoglobulin E receptor (FceRI).
Confezionamento: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Simbolo target: OX40;TNFRSF4
Ig target: Lck/Yes-related novel protein tyrosine kinase;Tyrosine-protein kinase Lyn (LYN);V-yes-1 Yamaguchi sarcoma viral related oncogene homolog;p53Lyn;p56Lyn and JTK8
Area di ricerca:Signal Transduction;
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