Immunoglobulin G (IgG) is a type of antibody composed of four peptide chains—two identical heavy chains and two identical light chains arranged in a Y-shape typical of antibody monomers.There are four IgG subclasses (IgG1, 2, 3, and 4) in humans, named in order of their abundance in serum. The IgG2a isotype was able to interact very efficiently with FcgammaR, and share approximately 64-78% amino acid sequence identity with IgG1 and IgG2b in the heavy chain constant region domains, CH1, CH2 and CH3, which cause the diffrence in the interaction with complement, NK and mast cells, induction or inhibition by specific cytokines, and ability to cross the placenta.

Codice: PKSR030448_10μg | Marca: Elabscience | Confezionamento: 10μg

Specie: Rat

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Codice: PKSR030448_10μg
Marca: Elabscience
Specie target: Rat
Host: HEK293 Cells
Confezionamento: Lyophilized from a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.5.<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
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Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Simbolo target: IgG2A Fc;Igg-2a
Ig target: Ig gamma-2A chain C region;Igg-2a

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