Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament (F-actin)-binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It may also play important roles in cell morphology and locomotion. Vinculin is a 117-kDa,1,066-amino-acid protein which is ubiquitously expressed. Its splice variant,metavinculin (124 kDa),is muscle-specific.

Codice: AN005300L_100μL | Marca: Elabscience | Confezionamento: 100μL

Specie: Human;Mouse;RatIsotipo: IgG1Clone: 4D4Coniugazione: Unconjugated

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Codice: AN005300L_100μL
Marca: Elabscience
Specie target: Human;Mouse;Rat
Host: Mouse
Concentrazione: 1 mg/mL
Link: Apri link
Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles. Protected from prolonged exposure to light.
Isotipo: IgG1
Clonalità: Monoclonal
Clone: 4D4
Coniugazione: Unconjugated
Applicazione: WB;IHC;IF
Diluizione: WB 1:2000-1:4000;IHC 1:200-1:400;IF 1:200-1:400
Simbolo target: Vinculin
Ig target: Vinculin;Metavinculin (MV);VCL
Area di ricerca: Cardiovascular;Signal Transduction;Isotype/Loading Controls;Epigenetics and Nuclear Signaling

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