This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.

Codice: AN200161P_100μL | Marca: Elabscience | Confezionamento: 100μL

Specie: HumanIsotipo: IgG1Clone: 3P12Coniugazione: Unconjugated

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Codice: AN200161P_100μL
Marca: Elabscience
Specie target: Human
Host: Mouse
Concentrazione: 1 mg/mL
Link: Apri link
Stoccaggio: This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
Isotipo: IgG1
Clonalità: Monoclonal
Clone: 3P12
Coniugazione: Unconjugated
Applicazione: ICC/IF
Diluizione: ICC/IF 1:20-1:100
Simbolo target: NTRK3
Ig target: NTRK;NTRK3;GP145-TrkC;TRKC;gp145(trkC);gp145(trkC)
Area di ricerca: Neuroscience;Cancer;Metabolism

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