The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.

Dettagli prodotto

• Codice: E-AB-10695_60μL
• Marca: Elabscience
• Specie target: Human;Mouse
• Host: Rabbit
• Concentrazione: 0.1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB
• Diluizione: WB 1:500-1:2000
• Simbolo target: ABCE1
• Ig target: 2' 5' oligoadenylate binding protein;2''-5''-oligoadenylate-binding protein;2'5' oligoadenylate binding protein;ABC 38;ABC38;ABCE 1;ABCE1;ABCE1;ATP binding cassette sub family E (OABP) member 1;ATP binding cassette sub family E member 1;ATP-binding cassette sub-family E member 1;HuHP 68;HuHP68;OABP;Ribonuclease 4 inhibitor;Ribonuclease L (2' 5' oligoisoadenylate synthetase dependent) inhibitor;Ribonuclease L (2'5' oligoisoadenylate synthetase dependent) inhibitor;Ribonuclease L inhibitor;RLI;RNase L inhibitor;RNASEL1;RNASELI;RNS 4I;RNS4I
• Area di ricerca: Cancer;Metabolism;Immunology;Signal Transduction