This protein plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. It can interacts with IL13RA1 and binds to microtubules, TRAF3 and DISC1.

Dettagli prodotto

• Codice: E-AB-14414_60μL
• Marca: Elabscience
• Specie target: Human;Mouse;Rat
• Host: Rabbit
• Concentrazione: 0.4 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB;IHC
• Diluizione: WB 1:500-1:2000;IHC 1:50-1:200
• Simbolo target: TRAF3IP1
• Ig target: Interleukin 13 receptor alpha 1 binding protein 1;Interleukin-13 receptor alpha 1-binding protein 1;Microtubule interacting protein that associates with TRAF3;Microtubule-interacting protein associated with TRAF3;MIP T3;MIP-T3;MIPT3;MIPT3;TNF receptor associated factor 3 interacting protein 1;TRAF3-interacting protein 1;Traf3ip1
• Area di ricerca: Immunology;Signal Transduction