Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation.

Dettagli prodotto

• Codice: E-AB-15139_120μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 0.5 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: IHC
• Diluizione: IHC 1:50-1:200
• Simbolo target: ITGAE
• Ig target: A530055J10;alpha-E1;alpha-M290;aM290;Antigen CD103;CD 103;CD103;CD103 antigen;HML 1 antigen;HML-1 antigen;HML1 antigen;Human mucosal lymphocyte antigen 1;Human mucosal lymphocyte antigen 1;alpha subunit;Huminae;Integrin alpha E heavy chain;Integrin alpha E light chain;Integrin alpha E;epithelial-associated;Integrin alpha E1;Integrin alpha IEL;Integrin alpha M290;Integrin alpha-E heavy chain;Integrin alpha-IEL;Integrin;alpha E (antigen CD103;human mucosal lymphocyte antigen 1;alpha polypeptide);Integrin;alpha E;ITAE;Itgae;MGC141996;MGC183601;Mucosal lymphocyte 1 antigen;Mucosal lymphocyte antigen 1
• Area di ricerca: Cancer;Immunology;Signal Transduction;Stem Cells