This gene encodes the alpha subunit of a transmembrane receptor for collagens and related proteins. The encoded protein forms a heterodimer with a beta subunit and mediates the adhesion of platelets and other cell types to the extracellular matrix. Loss of the encoded protein is associated with bleeding disorder platelet-type 9. Antibodies against this protein are found in several immune disorders, including neonatal alloimmune thrombocytopenia. This gene is located adjacent to a related alpha subunit gene. Alternative splicing results in multiple transcript variants.

Dettagli prodotto

• Codice: E-AB-15930_60μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 0.4 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB;IHC
• Diluizione: WB 1:200-1:1000;IHC 1:25-1:100
• Simbolo target: ITGA2
• Ig target: BR;CD 49b;CD49 antigen like family member B;CD49 antigen-like family member B;CD49b;CD49b antigen;Collagen receptor;DX5;Glycoprotein Ia deficiency included;GP Ia;GP Ia deficiency;included;GPIa;HPA 5 included;HPA5 included;Human platelet alloantigen system 5;Integrin alpha 2;Integrin alpha II;Integrin alpha-2;Integrin;alpha 2 (CD49B alpha 2 subunit of VLA 2 receptor);ITA2;ITGA2;Platelet alloantigen Br(a);included;Platelet antigen Br;Platelet glycoprotein GPIa;Platelet glycoprotein Ia;Platelet glycoprotein Ia/IIa;Platelet membrane glycoprotein Ia;Platelet receptor for collagen;deficiency of;included;Very late activation protein 2 receptor alpha 2 subunit;VLA 2 alpha chain;VLA 2;VLA 2 subunit alpha;VLA-2 subunit alpha;VLA2;VLA2 receptor alpha 2 subunit;VLAA2
• Area di ricerca: Cancer;Metabolism;Signal Transduction