Xenobiotic transporter that may play an important role in the exclusion of xenobiotics from the brain. May be involved in brain-to-blood efflux. Appears to play a major role in the multidrug resistance phenotype of several cancer cell lines. When overexpressed, the transfected cells become resistant to mitoxantrone, daunorubicin and doxorubicin, display diminished intracellular accumulation of daunorubicin, and manifest an ATP-dependent increase in the efflux of rhodamine 123.

Dettagli prodotto

• Codice: E-AB-30393_20μL
• Marca: Elabscience
• Specie target: Human
• Host: Rabbit
• Concentrazione: 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
• Isotipo: IgG
• Clonalità: Polyclonal
• Coniugazione: Unconjugated
• Applicazione: WB;IHC-p
• Diluizione: WB 1:500-1:2000;IHC 1:100-1:300
• Simbolo target: ABCG2
• Ig target: ABC transporter;ABC15;ABCG 2;ABCG2;ABCG2;ABCP;ATP binding cassette sub family G (WHITE) member 2;ATP binding cassette transporter G2;ATP-binding cassette sub-family G member 2;BCRP;BCRP1;BMDP;Breast cancer resistance protein;CD338;CDw338;CDw338 antigen;EST157481;GOUT1;MGC102821;Mitoxantrone resistance associated protein;Mitoxantrone resistance-associated protein;MRX;Multi drug resistance efflux transport ATP binding cassette sub family G (WHITE) member 2;MXR;MXR1;Placenta specific ATP binding cassette transporter;Placenta specific MDR protein;Placenta-specific ATP-binding cassette transporter;UAQTL1
• Area di ricerca: Cancer;Metabolism;Signal Transduction;Stem Cells;Tags and Cell Markers