GDP-L-Fucose Synthase is a NADP(H)-binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-dexoymannose to GDP-L-fucose. GDP-L-Fucose is the substrate of several fucosyltransferase, involving the expression of mamy glycoconjugates, including blood group ABH antigens and development adhesion antigens. Mutations in the TSTA3 gene may cause leukocyte adhesion deficiency type II.

Dettagli prodotto

• Codice: PKSH032483_50μg
• Marca: Elabscience
• Specie target: Human
• Host: E.coli
• Confezionamento: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
• Link: Apri link
• Stoccaggio: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
• Simbolo target: TSTA3;SDR4E1
• Ig target: 5-Epimerase-4-Reductase;GDP-4-Keto-6-Deoxy-D-Mannose-3;GDP-L-Fucose Synthase;Protein FX;Red Cell NADP(H)-Binding Protein;SDR4E1;Short-Chain Dehydrogenase/Reductase Family 4E Member 1;TSTA3
• Area di ricerca: Signal Transduction;metabolism;